Book review: 'Ozone: The Miracle Therapy'

Jed Stuber  ·  Jul 30, 2017

In order to help overcome illness and maintain ideal health, it is important to insure that the cells have an optimal supply of oxygen. Ozone therapy supplies the body’s cells with oxygen. Medical ozone therapy is a safe and effective way to treat many acute and chronic illnesses.  -- Dr. Brownstein

Scientists began experimenting with ozone, often called “activated oxygen,” in the 1800s, and it has been used in a wide variety of ways.

Ozone was used in World War I to treat gangrenous infections, and now is used as an anti-infection treatment by dentists. 

Many cities use it in their water treatment plants to reduce levels of viruses, parasites, metals, and the known carcinogen benzene. It’s also popular in home drinking systems and swimming pools.

In many countries today, including Germany, France, England, Italy, Canada, and Russia, ozone is widely used in medicine, but it hasn’t caught on as much in the U.S.

In Ozone: The Miracle Therapy, Dr. David Brownstein presents evidence that ozone has an impressive track record and should be used more often to treat a wide variety of maladies.

How ozone works in the body

According to Dr. Brownstein, ozone helps correct oxidant/anti-oxidant imbalances. He explains that  both oxidation and anti-oxidation processes in the body are important. Oxidation is often viewed as an entirely negative process, but it does play important roles, such as breaking down injured and old tissues as the first step in the process of regenerating them.

Ozone therapy stimulates BOTH oxidative and anti-oxidative pathways. Research shows that ozone therapy

  • improves circulation. 
  • improves oxygen delivery to tissues.
  • activates the immune system.
  • upregulates enzymes.

Similarly, hydrogen peroxide therapy has the benefits of regulating these body functions:

  • hormones, especially thyroid production.
  • membrane transport.
  • heat production.
  • energy production.
  • immune system.

Ways ozone therapy is done

Many people assume ozone therapy can only be done intravenously, but there are many methods.

For ulcers and infections there is “limb bagging,” which simply means wrapping a plastic bag around a limb and filling it with ozone gas.

Prolozone is a combination of procaine and ozone that is injected into the body. It helps restore oxygen flow to injured areas such as joints, ligaments, tendons, and muscles. Vitamins and minerals are also sometimes included in the mix.

Major Autohematherapy involves a patient’s blood being vacuum pumped into a bottle, ozonated, and then drained back into the body. It is used to treat autoimmune diseases, cancer, diverticulitis, heart disease, infections (including Lyme), macular degeneration, shingles, pneumonia, stroke, and urinary infections.

With Minor Autohematherapy a small amount of blood is mixed  with ozone in a syringe, and injected intravenously or intramuscularly.

Direct Intravenous Ozone Therapy refers to injecting ozone directly into the veins. Dr. Brownstein explains that it is controversial, and he cannot recommend it because of conflicting reports about its safety. A few doctors say it is safe and effective, but another well-respected ozone expert says there are credible reports that a few patients died from it.

There is also a technique known as insufflation, which means a catheter is inserted into a body cavity to allow it to fill with ozone. Bladder insufflation is used to treat urinary tract infections and cystitis. Rectal or vaginal insufflation is useful when a patient has poor venous access, and it can be done at home. Ear insufflation can treat ear infections, and the ozone can travel through the sinuses, treating sinus infections, tooth infections, and even upper respiratory infections. Ozone is also used orally by dentists to treat gum disease and infected teeth.

Ozone can also be injected intramuscularly to stimulate repair and regeneration mechanisms for injured or strained tissues. Sometimes it is only injected subcutaneously, under the skin, and Dr. Brownstein says he has found that particularly helpful for arthritis, sprains, and infections. Ozone is also injected into inflamed spinal discs to treat back pain.

The promise of ozone therapy

Dr. Brownstein includes chapters that go into more detail and give case studies about these topics:

  • Orthopedics: treatment of joint and bone issues, particularly in the knee, shoulder, and lower back.
  • Infections: osteomylitis, ebola, shingles, ear infections, Lyme disease, infectious arthritis, and hospital infections.

Dr. Brownstein also discusses cancer treatment. It has been known since the early 1900s that cancer thrives in low oxygen environments. More recent studies have revealed that the big difference between cancer cells and regular cells is how they produce energy. Cancer breaks down glucose without oxygen, while normal cells break down glucose with oxygen in the mitochondria. Tumors are essentially a “dysregulation of oxgen.” 

Since ozone is known to help regulate oxygen, Dr. Brownstein believes it has promise for treating cancer. He includes a case study of a cancer patient who experienced great improvement, but cautions that major studies have not been done to prove ozone’s effectiveness as a cancer treatment. Dr. Brownstein recommends it as adjunct cancer therapy, especially rectal insufflation.

If a determined lay person wants to delve into research on ozone and cancer, Dr. Brownstein recommends getting a copy of Ozone: A New Medical Drug by the Italian doctor Velio Bocci, which is considered the definitive resource on the topic, but a copy costs more than $200.

Dr. Brownstein also discusses hydrogen peroxide therapy, which produces the same effect: it increases oxygenation throughout the body. Studies have shown that it can stimulate fibroblast profliferation and new blood vessel growth.

Dr. Brownstein has treated hundreds of patients with intravenous hydrogen peroxide and seen dramatic improvements with pneumonia, cardiovascular disease, and gastrointestinal problems. Dr. Brownstein often uses ozone therapy, intravenous hydrogen peroxide, and intravenous vitamin C in conjunction.

Adverse effects, safety concerns?

After 20 years of treating thousands of patients, Dr. Brownstein says he has seen very few adverse affects, and even those are minor. A Herxheimer Reaction can occur in the same way as sometimes happens with antibiotic treatments. Patients experience fever, fast heart rate, and a drop in blood pressure. An experienced doctor can recognize it and make sure the patient gets proper hydration, rest, and nutrition until it passes. It does rid the body of infection, and patients often report feeling greatly improved after the reaction.

Another adverse effect of any intravenous therapy is the disappearance of veins. Again, it’s rare, and this condition can usually be mitigated by an experienced doctor.

Dr. Brownstein says that in his experience ozone therapy is completely safe, and he cites Bocci’s book because of his familiarity with the research and data available. Millions of therapy sessions are routinely performed across Europe with virtually no acute or chronic side effects reported.

Dr. Browstein hopes the medical community in the United States will start using and researching ozone more so it can be more widely available to the public. He recommends these organizations for finding a medical professional who does ozone therapy: International College of Integrative Medicine, Ozone Without BordersThe American Academy of Ozonotherapy, and The Society of Progressive Medical Education.

Editor’s Note: A limited number of therapy sessions may be shared only if related to the treatment of an injury or disease and if lawfully prescribed by a medical professional. See Guidelines VIII.B.36.

Dr. Brownstein is the Medical Director of the Center for Holistic Medicine in West Bloomfield, Michigan (

This article is for educational purposes and not meant as medical advice.